專利列表

2015年

國家  |  台灣     編號  |  I509070

用於預防或治療壓力引發之失調 

2015年

國家  |  日本     編號  |  特許第6035578號

乳酸菌、包含該乳酸菌的組合物以及其用途

Lactic Acid Bacterium, Composition Containing The Same And Their Use

2017年

國家  |  歐盟十四國     編號  |  EP2937424

乳酸菌、包含該乳酸菌的組合物以及其用途

Lactic Acid Bacterium, Composition Containing The Same And Their Use

2017年 

國家  |  南韓     編號  |  10-1813881

乳酸菌、包含該乳酸菌的組合物以及其用途

Lactic Acid Bacterium, Composition Containing The Same And Their Use

2018年

國家  |  台灣     編號  |  I623318

預防或治療功能性胃腸失調 

 

2018年

國家  |  台灣     編號  |  I623319

預防或治療運動障礙 

 

2018年

國家  |  中國     編號  |  ZL 2015 1 0195767.9

乳酸菌、包含該乳酸菌的組合物以及其用途

Lactic Acid Bacterium, Composition Containing The Same And Their Use

 

2019年

國家  |  美國     編號  |  US 10,188,684 B2

預防或治療內臟過度敏感、功能性胃腸失調、腹痛、便祕及腸躁症

The present invention provides a method for preventing or treating a functional gastrointestinal disorder in a subject in need thereof that includes a step of administering a composition, wherein the compostion includes an effective amount of Lactobacillus plantarum subsp. plantarum PS128 and a carrier. The present intervention futher provides a method for preventing or treating visceral hypersensitivity in a subject in need thereof that includes a step of administering a composition, wherein the composition includes an effective amount of Lactobacillus plantarum subsp. plantarum PS128 and a carrier. Moreover, the present inveention provides a method for preventing or treating funtional abdominal pain, irritable bowel syndrome or constipation in a subject in need there of that includes a step of administering  a composition, wherein the composition includes an effective amount of Lactobacillus plantarum subsp. plantarum PS128 and a carrier

獎項列表

2018  |  中國

錦獅獎 : 亞太精準醫療  -  年度益生菌全球領導品牌獎

主辦單位 : 亞太精准醫療聯盟、亞太精准醫學研究院聯合主辦;全球涉外高端醫療總會等協辦

2018  |  新加坡

Nutra Ingredients-Asia Awards  -  年度最佳益生菌產品

主辦單位 : Nutra Ingredients-Asia

備註 : Probiotic Product of the Year

2018  |  台灣

臺北生技獎  -  新創技術獎優等獎

主辦單位 : 台北市政府

2018  |  台灣

第十四屆國家新創獎  -  企業創新 農業及食品生技組

主辦單位 : 財團法人生技醫療科技政策研究中心

Research Center for Biotechnology and Medicine Policy

2017  |  美國

Fenox新創企業世界大賽(Startup World Cup)  -  台灣區冠軍

主辦單位 : Pegasus Tech Ventures

2017  |  台灣

第六屆女性創業菁英賽  -  新創組冠軍

主辦單位 : 經濟部中小企業處

2017  |  台灣

亞洲育成協會年會(Asian Association of Business Incubation, AABI)  -  火炬國際化獎 (Torch Award for Internationalization)

主辦單位 : 社團法人中華創業育成協會 

文獻列表

1.  Hui-Yu Huang, Shu-Ping Tsao, Long Term Supplementation of Lactobacillus plantarum PS128 Attenuated High-Intensity Exercise Induced Acute-Phase Inflammation in Triathletes, Current Developments in Nutrition, Volume 4, Issue Supplement_2, June 2020, Page 1564.

https://academic.oup.com/cdn/article/4/Supplement_2/1564/5844626  三鐵

2.  Liu YW, Liong MT, Chung YE, et al. Effects of Lactobacillus plantarum PS128 on Children with Autism Spectrum Disorder in Taiwan: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 2019;11(4):820.https://pubmed.ncbi.nlm.nih.gov/30979038/ 台灣自閉症男童

3.  Liao JF, Cheng YF, Li SW, et al. Lactobacillus plantarum PS128 ameliorates 2,5-Dimethoxy-4-iodoamphetamine-induced tic-like behaviors via its influences on the microbiota-gut-brain-axis. Brain Res Bull. 2019;153:59‐73.https://pubmed.ncbi.nlm.nih.gov/31351942/ 妥瑞式症鼠

4.  Liu YW, Wang YP, Yen HF, et al. Lactobacillus plantarum PS128 Ameliorated Visceral Hypersensitivity in Rats Through the Gut-Brain Axis [published online ahead of print, 2019 Nov 5]. Probiotics Antimicrob Proteins. 2019;10.1007/s12602-019-09595-w.https://pubmed.ncbi.nlm.nih.gov/31691208/ 腸躁症鼠

5.  Huang WC, Wei CC, Huang CC, Chen WL, Huang HY. The Beneficial Effects of Lactobacillus plantarum PS128 on High-Intensity, Exercise-Induced Oxidative Stress, Inflammation, and Performance in Triathletes. Nutrients. 2019;11(2):353.https://pubmed.ncbi.nlm.nih.gov/30736479/ 三鐵

6.  Liao PL, Wu CC, Chen TY, et al. Toxicity Studies of Lactobacillus plantarum PS128TM Isolated from Spontaneously Fermented Mustard Greens. Foods. 2019;8(12):668. Published 2019 Dec 11. doi:10.3390/foods8120668https://pubmed.ncbi.nlm.nih.gov/31835837/PS128 毒性


7.  Chang JS, Chiu YH, Pan CC, Chen CH: Probiotics Lactobacillus Plantarum PS128 intervention in two patients with major

depressive disorder. Taiwan J Psychiatry 2019; 33: 116-7.http://www.e-tjp.org/article.asp?issn=1028-3684;year=2019;volume=33;issue=2;spage=116;epage=117;aulast=Chang 重度憂鬰症病患個案分析

8.  Liu YW, Liu WH, Wu CC, et al. Psychotropic effects of Lactobacillus plantarum PS128 in early life-stressed and naïve adult mice. Brain Res. 2016;1631:1‐12. doi:10.1016/j.brainres.2015.11.018https://www.ncbi.nlm.nih.gov/pubmed/26620542 植物乳桿菌PS128對於早期生活壓力和正常成年小鼠的精神作用

9.  Liu WH, Chuang HL, Huang YT, et al. Alteration of behavior and monoamine levels attributable to Lactobacillus plantarum PS128 in germ-free mice. Behav Brain Res. 2016;298(Pt B):202‐209.https://pubmed.ncbi.nlm.nih.gov/26522841/ 無菌鼠的行為和單胺水平改變可歸因於植物乳桿菌PS128
 

10.  Liu WH, Yang CH, Lin CT, et al. Genome architecture of Lactobacillus plantarum PS128, a probiotic strain with potential immunomodulatory activity. Gut Pathog. 2015;7:22.https://pubmed.ncbi.nlm.nih.gov/26279684/ 基因

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